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Health & Science

Estimating the potential impact of global research on neglected tropical diseases on population-level indicators of health access, sanitation, and research capacity

Author summary The global rise in research on neglected tropical diseases, such as Chagas disease, leishmaniasis, and dengue, has raised important questions about its real-world effects. These diseases continue to affect poor communities, especially across Africa, Latin America, and Asia. Over the past decades, thousands of scientific papers have been published, yet uncertainty remains about whether this growing body of work has led to improvements in sanitation, healthcare access, and local scientific development. To explore this, a longitudinal analysis was conducted, linking published research on neglected tropical diseases with population-level indicators related to health access, sanitation, and research capacity. The findings revealed that progress has been uneven. Most research was produced by high-income countries, while improvements in key indicators were slower in low-income countries, where the burden of disease remains greatest. These results suggest that scientific output does not always translate into equitable health benefits. A better alignment between research priorities and the needs of affected populations appears essential to ensure that scientific progress contributes to real-world impact, especially in the most vulnerable settings.

Verified ContextSource-linkedAtlasHour DeskUpdated21 May, 12:00 amAI summary checked for clarity

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Author summary The global rise in research on neglected tropical diseases, such as Chagas disease, leishmaniasis, and dengue, has raised important questions about its real-world effects.

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PLOS (Public Library of Science)

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